Bufferin® contains three different antacids, including calcium carbonate, magnesium carbonate and magnesium oxide, which work together to help neutralize stomach acid and irritation associated with aspirin use.
No, do not take Bufferin if you are taking a blood thinning (anticoagulant) drug, steroid drug, or taking other drugs containing prescription or non-prescription NSAIDs (aspirin, ibuprofen, naproxen or others). Consult your doctor or pharmacist should you have any further questions or concerns regarding the use of Bufferin with other medication(s).
Aspirin reduces the production of hormone-like substances called prostaglandins, which are part of the chemical messenger systems involved in feeling aches and pains. Aspirin also works to temporarily reduce fever.
No, Bufferin® is not enteric coated, and it works faster than enteric coated aspirin. Enteric coating is designed to allow caplets to pass through the stomach to the small intestine before dissolving. This means it will take longer to take effect.
No. The buffering agents present in Bufferin® help to minimize stomach upset associated with aspirin use.
NSAIDs, including Bufferin, may cause severe stomach bleeding. The chance is higher if you are 60 or over, have had stomach ulcers or bleeding, take a blood thinning (anticoagulant) or steroid drug, take other NSAIDs, drink 3 or more alcoholic drinks every day while taking Bufferin, or use Bufferin for a longer time than directed. Stop taking Bufferin and talk to your doctor if you experience signs of stomach bleeding.

Be sure to read the entire Drug Facts labeling, including Use, Warnings, and Directions on the product package before use and use Bufferin only as directed.